Do not give this medicine to a child younger than 6 years old without the advice of a doctor. 400 this medication exactly as it was prescribed for you. Do not take the tablet in larger amounts, or take it for longer than recommended by your doctor, etodolac xl 400 mg tablet. Follow the directions on your prescription label. Do not crush, chew, etodolac break an extended-release tablet.
Swallow the pill whole.
It is specially made to release medicine slowly in the body. Breaking the etodolac would cause too much of the drug to be released at one time. It may take up to 2 weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed.
A history of heart attack, stroke, or blood clot A history of stomach tablets or bleeding Liver or kidney disease Polyps in your nose A bleeding or blood clotting 400 If you have any of these conditions, you may need a dose adjustment or special tests to safely take etodolac.
Pregnancy and Etodolac This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment.
Taking etodolac during the last three months of pregnancy may harm the unborn baby. Do not take etodolac during pregnancy unless your doctor has told you to. It is not known whether etodolac passes into breast milk or if it could harm a nursing baby. Gastrointestinal Effects — Risk of UlcerationBleeding, and Perforation NSAIDs, including etodolac capsules, etodolac xl 400 mg tablet, can cause serious gastrointestinal GI adverse events including inflammation, bleeding, ulceration, and perforation of the stomach, small intestineor large intestine, which can be fatal.
These serious etodolac events can occur at any time, with or without warning symptoms, in patients treated with NSAIDs. These trends continue with longer duration of use, increasing the likelihood of developing a serious GI event at some time during the course of therapy, etodolac xl 400 mg tablet. However, even short-term therapy is not without risk.
NSAIDs should be prescribed with extreme caution in those with a prior history of tablet disease or gastrointestinal bleeding. Other factors that increase the risk for 400 bleeding in patients treated with NSAIDs include concomitant use of oral corticosteroids or anticoagulants, longer duration of NSAID therapy, smoking, use of alcohol, older age, and poor general health status.
Most spontaneous reports of fatal GI events are in elderly or debilitated patients and therefore, special care should be taken in treating this population. To minimize the potential risk for an etodolac GI event in patients treated with an NSAID, the lowest effective dose should be used for the shortest possible duration.
Patients and tablets should remain alert for signs and 400 of GI ulceration and bleeding during NSAID therapy and promptly initiate additional evaluation and treatment if a serious GI adverse event is suspected.
Renal toxicity has also been seen in patients in whom renal prostaglandins have a compensatory role in the maintenance of renal perfusion, etodolac xl 400 mg tablet. In these patients, administration of a non-steroidal anti-inflammatory drug may cause a dose-dependent reduction in prostaglandin formation and, secondarily, in renal blood flow, which may precipitate overt renal decompensation. Patients at greatest risk of this reaction are those with impaired renal function, heart failure, liver dysfunction, those taking diuretics and ACEinhibitors, and the elderly.
Renal pelvic transitional epithelial hyperplasiaa spontaneous change occurring with variable frequency, was observed with increased frequency in treated male rats in a 2 year chronic study. Advanced Renal Disease No information is available from controlled clinical studies regarding the use of etodolac capsules in patients with advanced renal disease.
Therefore, treatment with etodolac capsules is not recommended in these patients with advanced renal disease.
If etodolac capsule therapy must be initiated, close monitoring of the patient's renal function is advisable. Anaphylactoid Reactions As with other NSAIDs, anaphylactoid reactions may occur in patients without prior exposure to etodolac capsules.
Etodolac capsules should not be given to patients with the aspirin triad.
This symptom complex typically occurs in asthmatic patients who experience rhinitis with or without nasal polypsor who exhibit severe, potentially fatal bronchospasm after taking aspirin or other NSAIDs. Emergency help should be sought 400 cases where an anaphylactoid reaction occurs. These serious events may occur without warning. Patients should be informed etodolac the signs and symptoms of serious skin manifestations and use of the drug should be discontinued at the first appearance of skin rash or any other sign of hypersensitivity.
Abrupt discontinuation of corticosteroids may lead to disease exacerbation. Patients on prolonged corticosteroid therapy should have their therapy tapered slowly if a decision is made to discontinue corticosteroids.
The pharmacological activity of etodolac capsules in reducing fever and inflammation may diminish the utility of these diagnostic signs in detecting complications of presumed noninfectious, painful conditions.
These laboratory abnormalities may progress, may remain unchanged, or may be transient cialis 20 mg 4 tablet fiyat� continuing therapy. In addition, rare cases of severe hepatic reactions, including jaundice and fatal fulminant hepatitisliver necrosis, and hepatic failure, some of them with fatal outcomes, have been reported.
If clinical signs and symptoms consistent with liver disease develop, or if systemic manifestations occur e. This may be due to fluid retention, occult or gross GI blood loss, etodolac xl 400 mg tablet, or an incompletely described effect upon erythropoiesis.
Missed Dose If you tablet a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage Store the medicine in a closed container at room temperature, away from heat, etodolac xl 400 mg tablet, moisture, and direct light.
Ask your healthcare professional how you should dispose of any medicine you do not use. Keep out of the reach of children. Do not keep outdated medicine or medicine no longer needed. Precautions Portions of this document last updated:
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